Medications
Tirzepatide with B12, semaglutide
Monthly Cost
$99-$299
Speed to Start
Fast
Compounded Medications
Est. 2019
About TRT Nation
TRT Nation entered the telehealth market in 2019 as a hormone replacement therapy provider and has since added GLP-1 weight management to its service menu. The platform offers compounded tirzepatide with B12 and compounded semaglutide, with monthly pricing between $99 and $299 — placing it at the more affordable end of the spectrum. The B12 combination formulation is a practical addition: vitamin B12 supports energy levels during caloric restriction and may help offset the fatigue some patients experience on GLP-1 therapy.
Trust metrics present a mixed picture that our editorial team weighs carefully. On Trustpilot, TRT Nation has just 14 reviews with a 2.2 rating, a sample size too small to draw definitive conclusions but concerning nonetheless. More significantly, the company holds an F rating with the BBB, the lowest possible grade, which indicates a pattern of unresolved consumer complaints. Prospective patients should approach with appropriate caution and thoroughly research current user experiences before committing to a treatment plan.
The clinical model is medium-support. TRT Nation provides lab testing as part of its hormone therapy protocols, and this diagnostic infrastructure carries over to its weight management patients. However, the platform’s GLP-1 program feels more like an add-on to its core TRT business than a fully developed weight management service. Patients should not expect the dedicated nutritional guidance, dose titration support, or behavioral coaching that high-support competitors provide.
The /month starting price is genuinely competitive, particularly for compounded tirzepatide, which typically commands higher pricing across the industry. If the clinical experience matches the price point, TRT Nation could represent real value for budget-conscious patients. The B12 combination also adds a functional benefit without additional cost. However, value is only meaningful when the underlying service is reliable, and the current trust indicators raise questions about consistency of care and customer service responsiveness.
TRT Nation occupies a difficult position in our rankings. The pricing is attractive and the medication options are relevant, but the F BBB rating and sparse Trustpilot presence make it hard to recommend with confidence. Patients who are already established TRT Nation clients for hormone therapy may find it convenient to add GLP-1 treatment through the same provider, but new patients specifically seeking weight management should consider providers with stronger trust profiles, even if it means paying more per month.
TRT Nation GLP-1 Medications
What the TRT Nation Intake Looks Like
We walked through TRT Nation’s full GLP-1 weight-loss intake ourselves — from the marketing quiz through every observable screen. Here’s what an actual prospective patient encounters before a prescription decision.
/ 10
The intake gates on BMI ≥25, age ≥25, and requires labs. Beyond that, the screening is shallow — no validated mental-health, eating-disorder, allergy, family-history, or comorbidity capture, and no FDA black-box (MTC/MEN2) screen despite tirzepatide being prescribed.
/ 10
Above average. Service is restricted to a subset of states (California is excluded), bloodwork is required at $129 (or BYO), and treatment + price are committed at Stage 1 before any clinical screen — including the BMI eligibility gate — has been completed.
The state dropdown at the start of the intake explicitly omits California and skips many other states alphabetically. Confirmed visible options include Arizona, Colorado, Connecticut, Delaware, Florida, Georgia, Illinois, Kansas, Maine, Minnesota, Missouri, Montana, New Mexico, New York, Ohio, Oklahoma, Pennsylvania, and Rhode Island — with multiple states absent between consecutive entries. Residents of California and any other unlisted state cannot complete the intake or be prescribed a GLP-1 by TRT Nation. Verify your state appears in the dropdown before considering this provider.
The 5 Stages
Clinical Safety Screens Performed
No FDA black-box screen for personal or family history of medullary thyroid carcinoma or MEN2 — a notable gap given tirzepatide carries this warning. No validated PHQ-2 or PHQ-9 depression screen, no dedicated eating-disorder screen, no allergy check, no comorbidity multi-select (heart, kidney, liver, cancer history), no family medical history, no medication interaction screen, and no USPSTF-style lifestyle-trial qualifier. The intake gates on BMI and age but otherwise relies on lab results and the downstream provider visit to surface contraindications.
Tirzepatide is presented at $219 on the treatment-selection screen, with fine print referencing an annual-supply price of $657 compounded with B12 covering doses from 2.5 mg to 15 mg with unlimited provider consults and free shipping. Phentermine is $99 for a 30-count, 37.5 mg supply. Bloodwork adds $129 if you don’t supply your own. Cash-pay only — no insurance is accepted at any tier.
Source: GLP-1.Reviews editorial walkthrough on April 26, 2026. We completed every observable screen of the TRT Nation weight-loss intake using a representative GLP-1 candidate persona and stopped before submitting payment information.
At a Glance
Medications Offered
Tirzepatide with B12, semaglutide
Compounded
Cost & Insurance
- Monthly: $99-$299
- 6-month estimate: $594-$1,794
- Insurance: No
- Self-pay: Yes
Clinical Features
- Lab testing: Yes
- Dietitian access: No
- Verified Pharmacy: Not disclosed
- BBB Rating: F
Delivery & Access
- Format: Subcutaneous
- Nationwide telehealth: No (state-limited — California excluded)
- Speed: Fast
- Spanish-speaking providers: Not available
Start your GLP-1 weight loss journey with TRT Nation today
Medical Disclaimer: This review is for informational purposes only and does not constitute medical advice. GLP-1 medications are prescription drugs that should only be used under the supervision of a licensed healthcare provider. Individual results may vary.
Editorial Independence: GLP-1.Reviews maintains full editorial independence. Our scores are based on verified data and standardized criteria.
