Medications
Semaglutide, Tirzepatide
Monthly Cost
$146 – $258
Speed to Start
Fast
Compounded Medications
Est. 2025
About Yucca Health
Yucca Health entered the GLP-1 telehealth market in 2025 and has quickly built an impressive volume of patient feedback, with over 970 reviews on Trustpilot and a strong 4.6-star rating. The platform offers compounded semaglutide and compounded tirzepatide at prices ranging from $146 to $258 per month, placing it among the more affordable options in the compounded medication space. For a relatively young company, the pace at which Yucca Health has accumulated positive reviews is noteworthy.
The Trustpilot profile tells an encouraging story about patient satisfaction, with the 4.6-star rating across nearly 1,000 reviews suggesting that the majority of customers have had positive experiences with the platform. This volume of feedback provides a more statistically meaningful picture than many competitors, and it indicates that Yucca Health is doing something right when it comes to basic service delivery and medication fulfillment. However, it is worth noting that the company does not yet have a Better Business Bureau listing, which limits one avenue of independent oversight.
One area where Yucca Health falls short is cost transparency. Our research flagged this as a notable weakness — prospective patients may find it difficult to determine exact pricing before committing to the platform. In a market where consumers are increasingly savvy about comparing costs across providers, a lack of upfront pricing clarity can erode trust and create frustration during the sign-up process. Providers that clearly display their pricing structure tend to perform better in our trust assessments.
Clinically, Yucca Health follows the common telehealth model of providing prescriptions without extensive wraparound support. The platform does not include lab testing or dietitian access as part of its standard program. While this keeps costs low, it does mean patients are largely on their own when it comes to monitoring health markers and implementing the dietary changes that maximize GLP-1 medication effectiveness. For patients who want a more comprehensive approach, this may be a limiting factor.
Overall, Yucca Health presents an interesting value proposition: affordable compounded GLP-1 medications backed by a high volume of positive patient reviews, tempered by limited clinical support and some transparency concerns. The strong Trustpilot performance distinguishes it from many competitors in the budget tier, but the lack of lab work, dietary support, and BBB accreditation keeps it from reaching the upper echelon of our ratings. It is a solid option for cost-conscious patients who are comfortable with a streamlined, medication-focused approach.
Yucca Health GLP-1 Medications
At a Glance
Medications Offered
Semaglutide, Tirzepatide
Compounded
Cost & Insurance
- Monthly: $146 – $258
- 6-month estimate: $880 – $1550
- Insurance: No
- Self-pay: Yes
Clinical Features
- Lab testing: No
- Dietitian access: No
- Verified Pharmacy: Greenwich Pharmacy (licensed U.S. compounding pharmacy); ships via UPS 2-Day Air
- BBB Rating: –
Delivery & Access
- Format: Subcutaneous
- Nationwide telehealth: Yes
- Speed: Fast
- Spanish-speaking providers: Not available
What the Yucca Health Intake Looks Like
We walked through Yucca’s full GLP-1 intake ourselves, from the modality picker through the dedicated allergy screens to the $0-today / approve-first-charge checkout. Here’s what an actual prospective patient encounters before being prescribed.
/ 10
Two dedicated allergy screens (GLP-1 brand-name + general drug/food/supplement), a dedicated diabetic drug-interaction screen with named medications, a structured current-meds block that captures dose and frequency, a dedicated bariatric-surgery screen, and a specific triglycerides > 600 mg/dL threshold. Knocked down by no validated PHQ, no dedicated eating-disorder or substance/alcohol screen, no BP reading, and no MTC/MEN2 family history items in the visible portion of the conditions list.
/ 10
Moderate. An email gate sits mid-flow at the pre-qualification reveal, account creation requires name + phone + ToS consent before any clinical question, and a 9:58-minute promo countdown timer runs on the shipping and payment screens. Friction is meaningfully softened by the $0-today / approve-first-charge mechanic at checkout.
The 9 Stages
Clinical Safety Screens Performed
The intake doesn’t use a validated PHQ-2 or PHQ-9 depression screen and doesn’t ask about self-harm. There is no dedicated eating-disorder screen with severity grading — anorexia / bulimia may exist below the fold of the medical-conditions multi-select but were not visible in our walkthrough. There is no substance or alcohol screen, no actual blood pressure or heart-rate reading, no diet or exercise history, and no MTC or MEN2 family-history items explicitly observed in the visible portion of the conditions list (pancreatic cancer is listed, but the FDA black-box family history isn’t called out separately). Sex is collected as a binary Male / Female only, with no separate gender identity question.
Yucca’s checkout uses an approve-first-charge mechanic that’s meaningfully more patient-friendly than the typical compounded-GLP-1 flow. The Order Summary copy reads: “A temporary authorization hold may appear on your card after checkout, but it won’t be charged unless your prescription is approved by a licensed provider.” The Pay button itself reads “Pay $0 Today,” and the included Free Medical Consultation (struck-through $150) plus Free Shipping & Handling (struck-through $19.95) make the financial commitment $0 if the prescription isn’t approved. Klarna and Affirm BNPL are both accepted for the post-approval charge. The promo countdown timer (9:58 minutes) on the shipping and payment screens is the one piece of pressure tactic that pulls in the other direction.
Source: GLP-1.Reviews editorial walkthrough on April 30, 2026. We completed every screen of the Yucca Health weight-loss intake using a representative GLP-1 candidate persona and stopped before submitting any payment information.
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Medical Disclaimer: This review is for informational purposes only and does not constitute medical advice. GLP-1 medications are prescription drugs that should only be used under the supervision of a licensed healthcare provider. Individual results may vary.
Editorial Independence: GLP-1.Reviews maintains full editorial independence. Our scores are based on verified data and standardized criteria.
