Medications
Compounded semaglutide with B6, Compounded tirzepatide with B6
Monthly Cost
Plans from $133/mo
Speed to Start
Fast
Compounded Medications
Est. 2023
About Brello Health
Brello Health entered the telehealth weight-loss market in 2023 with a distinctive angle: women-focused longevity medicine that pairs compounded GLP-1 medications with complementary vitamins. Their formulations combine compounded semaglutide or tirzepatide with vitamin B6, a nutrient involved in metabolism and neurotransmitter synthesis. Pricing starts at 3 per month, positioning Brello in the mid-range of the compounded market.
The B6 combination is Brello’s most talked-about differentiator. While the clinical evidence for adding B6 directly to a GLP-1 compound is still emerging, the company frames the inclusion within a broader longevity and metabolic optimization philosophy rather than treating weight loss as an isolated goal. That philosophy extends to their clinical intake, which screens for hormonal health markers and lifestyle factors that disproportionately affect women.
Patient volume on third-party review sites is impressive for a 2023 launch. Brello holds a 4.0-star rating across 3,300+ reviews on Trustpilot, suggesting strong early adoption and generally positive patient experiences. Common praise highlights attentive onboarding and clear dosing instructions, while negative reviews occasionally cite billing confusion and shipping timelines. The company does not currently hold a BBB accreditation.
From a clinical oversight perspective, Brello pairs patients with licensed providers who manage prescriptions and dosage titration. The women-focused branding is more than cosmetic: their intake questionnaires and provider consultations explicitly address hormonal fluctuations, perimenopause symptoms, and metabolic differences that generic telehealth platforms often overlook. For women who have felt underserved by one-size-fits-all weight-loss programs, that specificity is genuinely meaningful.
Our editorial team sees Brello Health as a promising newcomer with a clear niche. The B6 vitamin combo adds a layer of differentiation, the women-centric clinical model fills a real gap, and the early Trustpilot volume signals market traction. The lack of BBB listing and the company’s youth are the primary reasons we hold back from a higher score at this stage.
Brello Health GLP-1 Medications
At a Glance
Medications Offered
Compounded semaglutide with B6, Compounded tirzepatide with B6
Compounded
Cost & Insurance
- Monthly: Plans from $133/mo
- 6-month estimate: $798-$996
- Insurance: No
- Self-pay: Yes
Clinical Features
- Lab testing: No
- Dietitian access: No
- Verified Pharmacy: 503A USA-based partner pharmacy; Empower Pharmacy (for NAD+ products)
- BBB Rating: –
Delivery & Access
- Format: Subcutaneous
- Nationwide telehealth: Yes
- Speed: Fast
- Spanish-speaking providers: Not available
Start your GLP-1 weight loss journey with Brello Health today
Medical Disclaimer: This review is for informational purposes only and does not constitute medical advice. GLP-1 medications are prescription drugs that should only be used under the supervision of a licensed healthcare provider. Individual results may vary.
Editorial Independence: GLP-1.Reviews maintains full editorial independence. Our scores are based on verified data and standardized criteria.
What the Brello Health Intake Looks Like
We walked through the Brello Health funnel ourselves. The headline finding is that there is no public intake form at all — the funnel goes from product browse to product detail to a billing-and-shipping checkout in three clicks, with no eligibility quiz, no medical history, and not even a date-of-birth capture before the patient is asked for a credit card.
The lowest in our catalog, tied with Ask-RX. There is no public clinical screening of any kind — no BMI, no demographics, no medical history, no contraindications. The “Provider Health Review” line item in the bundle is the only reference to a clinical step, and it happens entirely after the $499 charge.
Moderate. The funnel itself is fast, but the 3-month minimum charges $499 today and another $499 every 10 weeks, and California patients are blocked at the state dropdown without any explanation.
The 3 Stages
When we reached the Billing & Shipping checkout form, California was missing from the state dropdown entirely. Brello does not surface a “we can’t ship to your state” rejection screen — it simply omits California from the list of selectable states, which means California-based patients who reach the billing form will encounter a silent dead end without any explanation. This is consistent with the broader pattern of compounded-GLP-1 platforms that exclude California due to its tighter compounding rules and physician supervision requirements, but the omission is unsigned: no banner, no callout, no apology, no waitlist link, no fallback content.
The Brello funnel is the most aggressive shopping-cart pattern we’ve audited. There is no eligibility quiz, no BMI, no demographics, no date of birth, no sex assigned at birth, no contraindication screen, no MTC/MEN-2, no pancreatitis, no pregnancy, no eating disorder, no mental-health screen, no substance use, no medical history, no current medications list, no allergy capture, no current GLP-1 overlap check, no family history, no BP or heart rate self-report, no ID upload, and no phone OTP. Even Lemonaid Health, Piper, and Ask-RX capture demographics or a phone number before reaching billing. Brello goes straight from a product card to a credit-card form. The “Provider Health Review” item in the included bundle is the only reference to clinical assessment, and it happens entirely after the patient has authorized the $499 charge.
The default Compounded Tirzepatide plan commits to $499 charged today and another $499 every 10 weeks, with a 3-month minimum and “cancel anytime” language. The cheaper Compounded Semaglutide plan starts at $133/month (also a 3-month minimum). The 33% savings call-out compares to a $749 strikethrough that does not appear to be a recently-charged price. Patients should also note the 3.5★ Trustpilot rating from 3,527 reviews — meaningfully lower than most peers in our catalog — and the explicit FDA compounded-drug disclaimer printed below the cart card.
Source: GLP-1.Reviews editorial walkthrough on April 14, 2026. We followed the Brello Health funnel from the GLP-1 Plans browse page through the product detail page to the Billing & Shipping checkout form, using a representative GLP-1 candidate persona, and stopped before submitting a credit card.
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