Last Updated: August 13, 2026
The 2026 GLP-1 landscape has evolved into a battle between two distinct care models: the comprehensive, flat-rate clinic and the flexible, brand-name marketplace. For consumers navigating the high costs of semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound), the choice between Mochi Health and Sesame often comes down to whether you value predictable compounded pricing or the direct transparency of a brand-name pharmacy network.
Mochi Health has established itself as a leader in the compounded medication space, offering a vertically integrated experience that includes dietitian support and flat-fee medications. On the other hand, Sesame functions as a healthcare marketplace, allowing patients to select providers and access brand-name medications through its clinical network.
This comparison breaks down the financial, clinical, and operational differences between Mochi Health and Sesame to help you determine which model fits your metabolic health journey.
Quick Comparison: Mochi Health vs. Sesame (2026)
| Feature | Mochi Health | Sesame Care |
|---|---|---|
| Membership Fee | $79/month | $99/month |
| Semaglutide Cost | $99/month (Compounded) | Not listed separately on the live review page |
| Tirzepatide Cost | $199/month (Compounded) | Not listed separately on the live review page |
| Prescriber Type | Specialist-led (Obesity medicine) | Marketplace-style provider network |
| Dietitian Support | Included in membership | Not included |
| Insurance | PA assistance noted | Accepts insurance |
| Medication Type | Primarily Compounded | Brand-name GLP-1 medications |
| Geographic Reach | All 50 states | All 50 states |
| Our Verdict | Top Tier (4.8) | Strong Choice (4.3) |
At-a-Glance: 3 Key Differences
- Compounded vs. Brand Name: Mochi Health is built around the 503A compounding model, providing flat-rate pricing regardless of dosage. Sesame focuses on brand-name GLP-1 medications including Ozempic, Wegovy, Zepbound, Mounjaro, Rybelsus, and Saxenda.
- Multidisciplinary Care: Mochi Health memberships include dietitian access and bariatric specialists. Sesame does not include dietitian access on its live review page.
- Pricing Structure: Mochi uses a subscription + flat medication fee. Sesame Care lists a flat $99/month program price on its live review page.
Pricing Comparison: The True Monthly Cost
When evaluating GLP-1 providers, the "membership fee" is only half the story. The total out-of-pocket (OOP) cost per month is the metric that matters for self-pay consumers.
Mochi Health Costs (Retrieved June 2026)
Mochi Health maintains a "dual-fee" structure. You pay for the membership to access the clinical team, and you pay a separate, flat price for the medication.
- Monthly Membership: $79
- Compounded Semaglutide: $99 (Any dose)
- Compounded Tirzepatide: $199 (Any dose)
- Total Monthly Cost (Semaglutide): $178
- Total Monthly Cost (Tirzepatide): $278
Mochi’s biggest advantage is dose-resiliency. As your dosage increases from 0.25mg to 2.4mg of semaglutide, your price stays exactly the same.
Sesame Costs (Retrieved August 2026)
Sesame Care lists a flat monthly program price on its live review page.
- Monthly Program Price: $99
- Lab Testing: Included
- Medication Pricing: Not separately listed on the live review page
- Insurance: Accepted
The Verdict on Value: Mochi Health remains the lower-cost option based on the live review-page pricing shown for compounded semaglutide and compounded tirzepatide. Sesame Care’s live review page supports a simpler flat $99/month program structure, but it does not list separate per-drug prices to enable a verified apples-to-apples medication cost comparison.
Drugs Available and Prescription Models
The clinical philosophy of these two platforms dictates the type of medication you receive.
Mochi Health: The Compounding Specialist
Mochi Health partners with 503A and 503B compounding pharmacies to ensure supply during national shortages. While they can prescribe brand-name medications like Zepbound or Wegovy to a local pharmacy, their "value proposition" is their internal pharmacy network.
- Compounded Semaglutide: Injectable and sublingual options.
- Compounded Tirzepatide: High-potency injectables.
- Brand Names: Available upon request, though patients must handle the pharmacy coordination and insurance hurdles independently.
Sesame: The Brand-Name Marketplace
Sesame Care focuses on brand-name GLP-1 medications rather than compounded options. This is a significant draw for patients who prefer established retail-pharmacy fulfillment paths or want a platform that accepts insurance.
- Medications Listed on the Live Review Page: Ozempic, Wegovy, Zepbound, Mounjaro, Rybelsus, Saxenda.
- Dietitian Access: Not included on the live review page.
Prescriber Model and Patient Flow
How you interact with your doctor differs significantly between these two platforms.
Mochi Health Flow:
- Signup: Extensive intake form covering medical history and weight loss goals.
- Provider Match: You are matched with a provider specialized in obesity medicine.
- Video Consultation: A mandatory face-to-face video call to discuss labs and dosing.
- Dietitian Call: You can schedule a separate session with a registered dietitian (included).
- Ongoing Support: Monthly check-ins via video or messaging.
Sesame Flow:
- Provider Selection: Unlike Mochi, Sesame allows you to browse a marketplace-style network of clinicians and choose the provider that fits your needs.
- Consultation: A telehealth visit is used to evaluate eligibility and treatment options.
- Lab Work: Lab testing is included.
- Prescription: If appropriate, prescriptions are sent through the standard pharmacy pathway.
- Follow-Up Access: Ongoing care is managed through the Sesame platform and provider network.
Geographic Availability and Customer Service
Both platforms have reached national scale by 2026, but their support structures vary.
- Geographic Reach: Both Mochi and Sesame operate in all 50 U.S. states.
- Customer Support: Mochi Health is known for its "Care Coordination" team, which acts as a concierge service for lab results and shipping issues. Sesame operates more like a tech platform, support is responsive, but you are often dealing with the individual provider’s office for clinical questions rather than a centralized care team.
Refund Policy and Safety
- Mochi Health: Offers a refund on the membership fee if you are not medically eligible for the program after your first visit. Medication, once shipped, is non-refundable.
- Sesame: Because Sesame is a marketplace, refund policies can vary by provider. However, the Sesame "Quality Guarantee" generally covers a refund for the visit fee if the patient is dissatisfied with the service.
Official Scoring and Methodology
At GLP-1 Reviews, we evaluate providers based on a rigorous, weighted scoring system. Our formula ensures that clinical quality and patient safety are prioritized over marketing hype.
Score = 0.22(Authenticity) + 0.18(Clinical) + 0.16(Trust) + 0.12(Reputation) + 0.10(Access) + 0.09(Support) + 0.08(Value) + 0.05(Protection).
Detailed information on our metrics can be found at our Review Methodology page.
Mochi Health: 4.8 (Top Tier)
Mochi Health is listed on its live review page as a Top Tier provider with a 4.8/5 score. The live review page also lists $79/month membership + $99/month compounded semaglutide or $199/month compounded tirzepatide, notes that no certificate of analysis (CoA) is offered, and states that dietitian access and bariatric specialists are included.
- Read the full Mochi Health Review.
Sesame: 4.3 (Strong Choice)
Sesame Care is listed on its live review page as a Strong Choice provider with a 4.3/5 score. The live review page lists $99/month pricing, states that lab testing is included, notes that Sesame accepts insurance, and says that Spanish-speaking providers are available. The same review page notes 4.5 Trustpilot across 3,700+ reviews. It also lists Ozempic, Wegovy, Zepbound, Mounjaro, Rybelsus, and Saxenda among the medication options, while dietitian access is not included.
- Read the full Sesame Review.
"Best for [Scenario]" Section
- Best for Cash-Pay Buyers: Mochi Health. If you are paying entirely out of pocket for injectables, Mochi’s $178/month semaglutide total is the lowest consistent price on the market.
- Best for Patients Who Want Dietitian Support: Mochi Health. The inclusion of registered dietitians ensures you aren't just losing weight, but also building sustainable habits.
- Best for Those Who Want Brand-Name Medication: Sesame. Its live review page centers on brand-name GLP-1 options including Ozempic, Wegovy, Zepbound, Mounjaro, Rybelsus, and Saxenda.
- Best for Patients Who Want Labs Included: Sesame. The live review page states that lab testing is included.
- Best for Patients Who Want Spanish-Speaking Providers: Sesame. The live review page notes availability of Spanish-speaking providers.
FAQ: Mochi Health vs. Sesame
Does Sesame offer compounded GLP-1s?
Based on the live review page, Sesame Care focuses on brand-name GLP-1 medications rather than compounded GLP-1s. Mochi Health is the primary choice in this comparison for patients seeking compounded semaglutide or compounded tirzepatide.
Is Mochi Health or Sesame better for insurance coverage?
Sesame Care has the clearer insurance position on its live review page because it explicitly states that it accepts insurance. Mochi’s live review details in this comparison emphasize its cash-pay membership plus compounded-medication model.
Can I use my own labs?
Yes, both platforms typically allow you to upload recent lab results (from within the last 6–12 months) to avoid additional costs.
Are there hidden fees?
Mochi Health is transparent on the live review details cited here: you pay the membership plus the listed compounded medication fee. Sesame Care’s live review page lists a flat $99/month program price, but it does not separately list medication prices in the review-page data used for this refresh.
What happens if there is a shortage?
Mochi Health may have an advantage during shortages because its model includes compounded medications through pharmacy partners. Sesame Care’s live review page focuses on brand-name GLP-1 access, so availability can depend more directly on standard retail-pharmacy supply.
Internal Resources
- 2026 GLP-1 Industry Statistics: The Definitive Data Report on Pricing
- Wegovy vs. Compounded Semaglutide: What’s the Real Difference?
- The GLP-1 Provider Directory
Corrected 8 October 2026. An earlier version of this comparison said our Mochi review notes that a certificate of analysis (CoA) is provided. That was our error: Mochi’s site does not offer one.
Corrected 9 October 2026. We removed a generated image from this article. Generated images on this site no longer show certifications, organisations, products, prices or figures unless the specific claim has been checked.
Corrected 13 October 2026. This article said Mochi Health claims LegitScript certification. Mochi’s own pages (read 7, 8 and 13 October 2026) make no such claim, so that has been removed. The claim came from our earlier Mochi review.
Corrected 14 October 2026: this article previously gave Better Business Bureau ratings for providers it compares, taken from our April 2026 research. We kept no record of where those ratings came from, so they have been removed.
Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice. Consult a licensed healthcare provider before starting any medication.
Keep exploring our GLP-1 resources:
