
Medications
Compounded semaglutide with B6, Compounded tirzepatide with B6
Monthly Cost
Plans from $133/mo
Speed to Start
Fast
Compounded Medications
Est. 2023
About Brello Health
Brello Health entered the telehealth weight-loss market in 2023 with a distinctive angle: women-focused longevity medicine that pairs compounded GLP-1 medications with complementary vitamins. Their formulations combine compounded semaglutide or tirzepatide with vitamin B6, a nutrient involved in metabolism and neurotransmitter synthesis. Pricing starts at 3 per month, positioning Brello in the mid-range of the compounded market.
The B6 combination is Brello’s most talked-about differentiator. While the clinical evidence for adding B6 directly to a GLP-1 compound is still emerging, the company frames the inclusion within a broader longevity and metabolic optimization philosophy rather than treating weight loss as an isolated goal. That philosophy extends to their clinical intake, which screens for hormonal health markers and lifestyle factors that disproportionately affect women.
Patient volume on third-party review sites is impressive for a 2023 launch. Brello holds a 4.0-star rating across 3,300+ reviews on Trustpilot, suggesting strong early adoption and generally positive patient experiences. Common praise highlights attentive onboarding and clear dosing instructions, while negative reviews occasionally cite billing confusion and shipping timelines. The company does not currently hold a BBB accreditation.
From a clinical oversight perspective, Brello pairs patients with licensed providers who manage prescriptions and dosage titration. The women-focused branding is more than cosmetic: their intake questionnaires and provider consultations explicitly address hormonal fluctuations, perimenopause symptoms, and metabolic differences that generic telehealth platforms often overlook. For women who have felt underserved by one-size-fits-all weight-loss programs, that specificity is genuinely meaningful.
Our editorial team sees Brello Health as a promising newcomer with a clear niche. The B6 vitamin combo adds a layer of differentiation, the women-centric clinical model fills a real gap, and the early Trustpilot volume signals market traction. The lack of BBB listing and the company’s youth are the primary reasons we hold back from a higher score at this stage.
At a Glance
Medications Offered
Compounded semaglutide with B6, Compounded tirzepatide with B6
Compounded
Cost & Insurance
- Monthly: Plans from $133/mo
- 6-month estimate: $798-$996
- Insurance: No
- Self-pay: Yes
Clinical Features
- Lab testing: No
- Dietitian access: No
- Verified Pharmacy: 503A USA-based partner pharmacy; Empower Pharmacy (for NAD+ products)
- BBB Rating: –
Delivery & Access
- Format: Subcutaneous
- Nationwide telehealth: Yes
- Speed: Fast
- Spanish-speaking providers: Not available
Start your GLP-1 weight loss journey with Brello Health today
Medical Disclaimer: This review is for informational purposes only and does not constitute medical advice. GLP-1 medications are prescription drugs that should only be used under the supervision of a licensed healthcare provider. Individual results may vary.
Editorial Independence: GLP-1.Reviews maintains full editorial independence. Our scores are based on verified data and standardized criteria.













