Compounded semaglutide and tirzepatide offer a more affordable path to GLP-1 treatment, but not all compounders are equal. We highlight Certificate of Analysis (CoA) testing status and pharmacy transparency because injectable medication quality depends on manufacturing standards.
Ivim Health
Ivim Health is the highest-scoring provider in our directory, and it earns that distinction through a combination of clinical excellence, transparency, and patient satisfaction that few competitors...
Mochi Health
Mochi Health has quickly become one of the most talked-about GLP-1 providers in the telehealth space, and for good reason. Founded in 2022, the platform combines affordable compounded medications w...
Fridays Health
Fridays Health takes a holistic approach to GLP-1 weight loss by pairing medication with a fitness app, dietitian access, and insurance support — a combination that few competitors offer at this pr...
eMed
eMed entered the telehealth space in 2020 and quickly gained recognition during the COVID-19 pandemic for its at-home testing infrastructure. The company has since pivoted that diagnostic capabilit...
LifeMD
LifeMD stands out in the crowded GLP-1 telehealth space by combining a broad medication menu with metabolic lab testing and a weight loss guarantee — a confidence signal that few competitors are wi...
Noom
Noom built its reputation on a psychology-based approach to weight management long before GLP-1 medications entered the mainstream. Founded in 2008, the platform has helped millions of users develo...
Found
Found differentiates itself through a science-forward approach anchored by their proprietary MetabolicPrint assessment — a personalized metabolic profiling tool that aims to match patients with the...
Prices and medications are as listed when each review was captured, mostly April 2026, and have not been re-checked since. Each review gives its date.
We may earn a commission if you purchase through links on this page, at no additional cost to you. This helps support our work.
How we rank: Providers are ranked by our weighted scoring methodology across 8 categories. Rankings update automatically as new providers are reviewed and scores change. To learn more, visit our Review Methodology page.
Disclaimer: This comparison is for informational purposes only and does not constitute medical advice. Always consult your doctor before starting any GLP-1 medication.
How to Choose a Compounded Semaglutide Provider
Compounded semaglutide and tirzepatide are the most affordable path to GLP-1 treatment, but manufacturing quality and clinical oversight vary widely. Four things separate a trustworthy compounded provider from a risky one:
- A batch Certificate of Analysis — ask for one: it shows that your batch was tested for potency and purity. None of the compounding providers we review publishes one.
- Pharmacy transparency — look for named pharmacies you can look up (a 503B outsourcing facility on FDA’s register, or a state-licensed 503A pharmacy) rather than vague claims.
- Clinical screening depth — a proper intake screens for thyroid cancer and MEN-2 history, not just a checkbox.
- Ongoing support — included lab testing and dietitian access matter more than the sticker price.
Our top-rated compounded provider, Ivim Health (4.9/5), pairs published clinical research with included lab testing, dietitian access and insurance acceptance — at $149/mo it is also strong value. If clinical-screening rigor is your priority, Trim RX runs one of the most thorough safety intakes we have seen among compounded platforms (personal and family history for medullary thyroid cancer and MEN-2), though it is cash-pay only and pricier at $174-$449/mo. Midi Health is a strong insurance-friendly middle ground.
